BPC-157 (5mg) – BC05

BPC-157 (5mg) — Research Peptide

BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide comprising 15 amino acids, derived from a partial sequence of a protective protein isolated from human gastric juice. It has been the subject of extensive preclinical research across gastrointestinal, musculoskeletal, neurological, and dermal biology, making it one of the most broadly studied research peptides in the published literature.

Mechanism of Action

BPC-157’s documented biological activity operates through multiple pathways. Primary among these is upregulation of the VEGFR2-Akt-eNOS signalling axis, which drives angiogenesis — the formation of new blood vessels — at injury sites. Enhanced vascular supply is a prerequisite for tissue repair, and BPC-157’s consistent pro-angiogenic effects across multiple animal models have made it a key research compound in wound healing science.

Additionally, BPC-157 modulates the expression of early growth response protein 1 (EGR1), a transcription factor that governs tendon-specific collagen gene expression. Studies by Sikiric et al. have documented accelerated tendon-to-bone healing in rat transection models, with histological analysis confirming increased collagen density and organisation at repair sites. The compound also influences nitric oxide (NO) synthesis pathways and has demonstrated cytoprotective effects in gastrointestinal epithelium exposed to NSAID-induced damage.

Research Applications

Published research has investigated BPC-157 across several domains:

• Musculoskeletal: Tendon and ligament transection models, muscle crush injuries, bone repair
• Gastrointestinal: Ulcer and colitis models, mucosal protection, gut motility
• Neurological: Dopaminergic and serotonergic system modulation, spinal cord injury models
• Dermal: Fibroblast proliferation, wound closure rate, angiogenesis in skin repair models

Product Specifications

• Peptide: BPC-157 (Body Protection Compound-157)
• Dose: 5mg per vial
• Format: Lyophilised powder, bulk box of 10 vials
• Purity: ≥98% verified by Janoshik third-party HPLC analysis
• Testing: Each batch tested for purity, sterility, endotoxin, and heavy metals
• Storage: Store at -20°C. Stable for 24 months lyophilised.

For laboratory research use only. Not for human therapeutic use. All products sold by Eternal Peptides Supply comply with Australian research peptide regulations.